Linalool
ลินาลูลSoft, floral, and sweet — the signature scent of lavender. Calming and soothing.
โปรไฟล์กลิ่น
สรรพคุณทางการแพทย์
Anti-anxiety
หลักฐานแข็งแกร่งNMDA receptor blockade; serotonin reuptake inhibition; enhanced GABAergic currents 2–7 fold
Linalool enhanced GABAergic currents 2–7 fold, explaining its anxiolytic and sedative effects.
Silexan (80 mg linalool) was as effective as paroxetine 20 mg for GAD — the gold-standard SSRI.
Sedative
หลักฐานแข็งแกร่งIncreases adenosine (sleep neurotransmitter); GABAergic modulation
Linalool odor activated GABAergic pathways producing anxiolytic effects without motor impairment.
Analgesic
หลักฐานปานกลางNMDA receptor antagonism; opioid and cholinergic pathway modulation
Linalool produced antinociception in both glutamate-induced and formalin-induced pain models.
ปฏิสัมพันธ์ (Entourage Effect)
Enhanced anti-anxiety and anti-inflammatory effects
preclinicalCombined sedative effects for enhanced sleep
clinical (JCSM 2025)