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Bisabolol
Sesquiterpene alcoholDelicate, sweet floral with chamomile-like and slightly nutty notes. Gentle and soothing.
Aroma Profile
floral sweet nutty
Medical Effects
Anti-inflammatory
Strong evidenceMechanism
Inhibition of pro-inflammatory cytokines TNF-alpha and IL-6; NF-kB pathway modulation
Supporting studies
Alpha-bisabolol reduces pro-inflammatory cytokine production
Kim, S. et al.
Curr Drug Metab (2014)
Significantly inhibited LPS and TPA-induced TNF-alpha and IL-6. Dose-dependent inflammation reduction.
Analgesic
Moderate evidenceMechanism
Anti-nociceptive; reversal of mechanical sensitization in neuropathic pain models
Supporting studies
Pharmacological effects of alpha-bisabolol
Various
Life Sci (2022)
Alpha-bisabolol reversed mechanical sensitization in infraorbital nerve transection model.
Skin healing
Strong evidenceMechanism
Enhances percutaneous absorption; direct wound healing properties
Synergies (Entourage Effect)
+
Bisabolol + CBD
Enhanced anti-inflammatory and skin-healing effects
preclinical+
Bisabolol + Linalool
Combined calming and skin-soothing properties
traditional use
