Myrcene
MonoterpeneEarthy and musky with herbal, clove-like undertones. The baseline scent of cannabis.
Aroma Profile
Medical Effects
Anti-inflammatory
Strong evidenceInhibition of cyclooxygenase (COX) pathways; anticatabolic effects in osteoarthritis models
Myrcene (1–5 mg/kg) reduced joint pain and inflammation via a cannabinoid receptor mechanism in rats.
Analgesic
Strong evidenceOpioid receptor pathway (blocked by naloxone); no tolerance observed after repeated dosing
Significant analgesic effect blocked by naloxone. No tolerance after repeated dosing.
Myrcene mimics lemongrass tea's peripheral analgesic activity.
Sedative
Moderate evidenceProlonged sleep time, reduced REM sleep, increased non-REM sleep
Myrcene prolonged sleep time and increased non-REM sleep. At high doses, effects comparable to phenobarbital.
Synergies (Entourage Effect)
May enhance THC absorption across blood-brain barrier, increasing potency
preclinicalCombined anti-inflammatory and analgesic effects
preclinical
